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Abstract on ASLAN Pharmaceuticals’ Varlitinib Accepted for Poster Presentation at ESMO Asia Congress 2019
Data comparing the therapeutic response between varlitinib plus capecitabine and lapatinib plus capecitabine by analyzing the changes of tumor volume per tumor location in patients with HER2-positive metastatic breast cancer after trastuzumab therapy will be presented.
The abstract (Abstract #681), titled ‘The challenge of evaluating new targeted therapies: Opportunities in stratifying the therapeutic response per tumor location’, will be available online at https://www.esmo.org/Conferences/ESMO-Asia-Congress-2019 on 19 November,
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About varlitinib (ASLAN001)
Varlitinib (ASLAN001) is a highly potent, oral, reversible, small molecule pan-HER inhibitor that targets the human epidermal growth factor receptors HER1, HER2 and HER4. These receptors can be mutated or overexpressed in many tumours, which can cause excessive proliferative activity and uncontrolled growth. Therefore, by inhibiting the activation of the HER receptors, varlitinib could inhibit proliferation and control tumour growth. Varlitinib has been granted orphan drug designation in
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Source: ASLAN Pharmaceuticals Limited